Reuters OFweek medical technology with the development of life sciences, a growing awareness of the depth of genes, "genes" the word evolved over a century, may have a more precise explanation from the molecular level. The study of the historical origin of genetic concepts can not only reveal the mystery of life phenomena in essence, but also promote the development of fields with "life" phenomena such as business and the Internet.
On November 14th, the “OFweek 2017 (2nd) China Medical Technology Conference†hosted by OFweek China High-Tech Industry Portal and the High-Tech Association, and held by OFweek Medical Technology Network, was held in Shenzhen. In this context, in the keynote speech "Gene + Internet, Accurate Health Starts with Me", Guan Xin, deputy general manager of Huada Gene Internet Center, shared the research results of the gene + Internet field and its development direction.
Guan Xin, deputy general manager of Huada Gene Internet Center
The origin and difference of genes
The word gene comes from the Greek word for "life." Refers to a DNA or RNA sequence carrying genetic information, which is the basic genetic unit that controls the trait, that is, a functional sequence. Genes control the expression of proteins by directing the synthesis of the genetic information they carry, thus controlling the performance of the individual's traits. Humans have about 20,000 to 25,000 genes scattered throughout the somatically existing chromosomes, each with a certain number of genes. Guan Xin said that each of us is composed of the four most basic letters, ATCG. If we use a pair of playing cards, it is black and red.
In the process of human evolution, the nuances of DNA have created the diversity of nature, and the choice of genes is different, and the characteristics exhibited by the human body are different, such as double eyelids and single eyelids, rolling tongues and not being able to roll tongues.
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In the process of constant selection and change of genes, there will also be mutations in the gene. The mutations in the gene are good or bad, such as sickle-type anemia, which is caused by mutations in the DNA of the hemoglobin β gene.
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The relationship between genes and diseases
So what is the use of genetic research? Guan Xin explained: "In addition to the phenotypic factors we have seen above, there is also an inseparable relationship between genes and diseases. Diseases are affected by genetic and environmental factors, and some diseases, such as thalassaemia and dwarfness. Symptoms, which are closely related to genes, because they are single-gene diseases, single genes or two genetic mutations from parents can cause diseases; and one type is complex diseases, such as most chronic diseases, tumors, etc., genetically, Living environment, eating habits and other factors affect."
Future development of genetic medicine
The disease-causing gene is innate, and it will gradually manifest itself with the induction of the environment, gradually forming diseases, such as tumors. The tumor did not happen suddenly, but was suddenly discovered. From early adenomas to advanced invasive cancers often take years or decades. The cause of malignant tumors, in addition to the mutations caused by self-aging, some of the human oncogenic mutations and external environment-induced mutations may form malignant tumors. Conventional tumor screening often only finds advanced cancer, and misses the best time for tumor detection.
In response to these problems, Guan Xin said: "Precise detection + precise intervention mode will enable you to better understand your genetic status, so you can delay the time of disease gene expression by preventing or preventing the drug in advance."
Finally, Guan Xin added: "Life is digital, gene + Internet + big data + artificial intelligence, will provide you with personalized accurate health advice, guidance, products, programs, it will also be the future development direction of precision medicine ."
For more details, please pay attention to the follow-up reports of OFweek Medical Technology Network!
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