British biotech company says breakthrough in human research on porcine organ transplantation

London, August 23rd: A British biotechnology company said that they have made breakthroughs in the study of transplanting human organs from pigs. The BBC reported today that the PPL company, headquartered near Edinburgh, the capital of Scotland, said that for the first time they had bred pigs that completely ruled out a "harmful gene," and transplanted the pig's organs to humans without causing rejection. Scientists reacted differently to the company’s statement. Some people say that this is "significant progress," while others believe that the outcome is far from the ultimate goal. In addition, the PPL company submitted its research report to news organizations rather than published in professional scientific journals, which also caused criticism. Professor McLean at the University of Glasgow said: “This is obviously a major advance. If the results are widely used, it will certainly reduce many practical problems in organ transplantation.” However, Beit, head of animal genetic modification research group of the Royal Society of Britain Professor Sen said: "The scientific community was skeptical before the study was carefully evaluated by its peers in the field." Roger, a director of the UK transplant research project, was also cautious. He said: "Although this is an interesting development, there are still many studies to be done before confirming whether it can be successfully transplanted into the human body." He fears that the virus infected by swine may be transmitted to humans. Over the years, scientists have been trying to use GM technology to breed pigs that can be used for human organ transplants, because transplanted organs donated by humans are extremely scarce, and pigs can be a reliable source of transplanted organs. However, pigs can produce a special sugar that can cause the body's immune system to produce rejection. The key to preventing rejection is to exclude a gene that places this particular sugar on the surface of pig cells. PPL claims that they have cultivated a pig that has excluded the gene.

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