My scientist confirmed genes related to breast cancer

Release date: 2006-11-08

My scientists have confirmed the genes related to breast cancer according to the Science and Technology Daily (Reporter Ma Bo) Recently, a new viewpoint and diagnosis model for detecting breast cancer, tumor suppressor gene abnormality prediction and early diagnosis of breast cancer by domestic benign breast lesions 14 unit applications. This achievement was jointly completed by the Kunming General Hospital of the People's Liberation Army, the Kunming Institute of Zoology, Chinese Academy of Sciences, and the First Affiliated Hospital of Kunming Medical College.
The current diagnosis of breast cancer relies on pathological examination. That is, after the patient finds a long mass of the mammary gland, a small piece of specimen is removed for pathological diagnosis. However, when breast cancer is detected according to the current international pathological criteria, it is often late. Therefore, research on the technique of early diagnosis of breast cancer more than conventional pathological examination has become a subject of thinking and conquering by scientists and technicians. The project "Molecular Pathology of the Role of Oncogenes and Tumor Suppressor Genes in Breast Cancer Development" came into being.
Scientists start with what genes play a role in breast cancer formation, hoping to find genes involved in breast cancer and clarify the changes in these genes.
In collaboration with the University of Nebraska Medical School, the researchers used the hospital's breast cancer model to select the two oncogenes and 10 tumor suppressor genes most likely to be associated with breast cancer, using molecular biology techniques. Up to 8 years of research experiments. It was finally confirmed that the two selected oncogenes and seven tumor suppressor genes played an important biological role in the development of breast cancer, thus confirming the dysplasia of breast cancer as the essence of precancerous lesions of breast cancer at the molecular level. Early diagnosis of breast cancer provides an important experimental basis. For the first time, new ideas and diagnostic models for predicting and early diagnosis of breast cancer by detecting abnormal genes of oncogenes and tumor suppressor genes in benign breast lesions have been proposed. At present, the results have been applied to postgraduate pathology teaching and prognosis diagnosis of breast cancer proliferative diseases by 14 units in China, and also provide a basis for the development of breast cancer treatment drugs.
The head of the research team and director of the Department of Pathology of the Kunming General Hospital of the People's Liberation Army told Yang that the breast cancer is growing at an annual rate of 0.3%-8%, which is the first killer of female cancer patients. The completion and continued research of the project has important theoretical and practical value for the diagnosis and prevention of breast cancer and the development of tumor pathology.
Source: Technology Daily

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