Regulatory proteins against "invasion" were discovered
July 26, 2018 Source: Health News
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Professor Wang Xiaoming from the Department of Immunology of Nanjing Medical University found a key regulatory protein against the pathogen "Uhrf1". With it, the human immune system can quickly cultivate a "combat force" to deal with pathogens. The research results have recently been published in the journal Journal of Experimental Medicine in the field of medical immunology.
According to reports, the human immune system receives the "invasion" signal, the first time will be a "combat force" in the human body - antibodies are counted, control the antibody to produce key human B cells, after receiving the command, it begins Self-preparation, if the power is not enough to fight the virus, a new round of "conscription" will be issued to activate the antigen in the body to collect enough powerful antibodies. However, before the battlefield, the original antigens in the body need to be recombined in order to better fight.
Wang Xiaoming's research team found that Uhrf1 protein is the key to affecting B cells to stand out in the boot camp and get a certificate quickly. Once the Uhrf1 protein is missing, as the quality of the emergency levy is not enough, the rapid growth of the soldiers in the boot camp will be hindered, and it will also affect whether they can quickly become qualified soldiers. The research team also found that the impact of this quality on the growth of soldiers was mainly caused by the first period of the growth of recruits, that is, the critical period when recruits faced elimination. Once there is insufficient power growth, the number of recruits entering the second round of selection will be greatly reduced.
Chen Chao, a member of the research team, said that the discovery of this achievement suggests that researchers should pay attention to and consider the role of Uhrf1 protein in the future development of vaccines, so that they can quickly and effectively train a strong combat capability, technical precision, and psychology. The high-precision "high-precision" units that are able to pass the quality are more effective in combining antibodies to protect human health. (Reporter Cheng Shouqin correspondent Zhang Yanhui Chen Siyu)
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