The pharmacological effects of gentian

Pharmacological effects

1. Effect on digestive tract Gentian or gentian buckwheat can promote the secretion of gastric juice and gastric acid. Oral administration of gentian buckwheat to dogs with gastric fistula can promote secretion of gastric juice and increase free hydrochloric acid and increase appetite. The sublingual smear or intravenous injection is not effective, so it is believed that gentian buckwheat can directly promote the secretion of gastric juice and increase free acid.

2. Gallbladder and hepatoprotective effects Health and liver damage mice, duodenum 50g/kg gentian injection or intravenous injection of 4.5g/kg healthy dogs, can significantly increase bile flow. From the canine biliary secretion flow curve, two peaks appeared at 5 minutes and 20 minutes of administration. Gentian injection 25g/kg subcutaneous injection, α-naphthalene isothiocyanate induced experimental jaundice model (hyperbilirubinemia and cholestasis), can significantly reduce the serum bilirubin content.

3. The diuretic effect of gentiozide injection 10g/kg, ear vein injection, can make 5 rabbits from the average urinary volume per 30 minutes before administration increased to 2.64ml (p <0.1), suggesting that gentian has obvious diuresis effect.

4. Antimicrobial effect test 14 types of Gentian plants, of which 7 pairs of nodule bacteria, E. coli, Bacillus subtilis, Agrobacterium tumefaciens, etc. have a role. Gentian turfgrass inoculants in vitro have different degrees of inhibitory effect on trichomonas vaginalis and other dermatophytes. The test tube method proved that the gentian decoction had different degrees of inhibitory effect on Pseudomonas aeruginosa, Proteus, Salmonella typhi, Shigella, Staphylococcus aureus and so on.

5. The role of the central nervous system gentisine on the central nervous system in mice excited, but there is an anesthetic effect at higher doses. Swertia sclerophylla inhibits the central nervous system and has analgesic and sedative effects. Has antispasmodic effect on intestinal and uterine smooth muscle

6. Other effects When taken in large quantities, it can interfere with digestion, headache, facial flushing, and dizziness. The chemotherapeutic test with gentian (unspecified) has been used in mice with Ehrlich ascites carcinoma, demonstrating antitumor effects. The high dose of gentian has antihypertensive effect on anesthetized animals and can inhibit the heart and slow down the heart rate. The Gentiopicroside proposed in G. lutea is highly toxic to Plasmodium falciparum for malaria fever and antibacterial formaldehyde arthritis. Gentraline has antihypertensive effects on cats and has anti-inflammatory effects on rat arterial arterial edema in rats. Gentiana aqueous extract inhibited chloropicrin-induced delayed-type hypersensitivity in mice.


SILCA VIPER KEY MILLING CUTTER SERIES

SILCA VIPER KEY MILLING CUTTER SERIES

End mill cutter and tracer point for Silca Viper

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