Gene editing technology is becoming a weapon for humans to fight against incurable diseases.
On October 12th, local time, a paper on the use of CRISPR-Cas9 technology to treat sickle cell anemia was published in the American academic journal Science·Transformation Medicine. A team of researchers at the University of California, Berkeley and San Francisco, and the University of Utah, using CRISPR-Cas9 technology to successfully repair disease-causing mutations in stem cells in vitro, provides a potential treatment for sickle cell anemia.
Sickle cell anemia is a genetic disease caused by a mutation in a gene in a blood cell, which causes the hemoglobin molecules responsible for carrying oxygen to stick together, making the cells sickle-shaped, hence the name. These sickle-shaped deformed cells can cause blood vessels to clog and fail to deliver oxygen to the tissue, causing symptoms such as anemia, pain, and even organ failure.
According to statistics, about 250,000 newborns worldwide have congenital sickle cell anemia every year. African Americans and people living in sub-Saharan Africa have long been afflicted with sickle cell anemia. Humans have been fighting with it for more than 65 years, and the addition of CRISPR-Cas9 gene editing technology has given humans new weapons against sickle cell anemia.
The so-called gene editing technology refers to the "reconstruction" of the target gene by human beings, achieving the knockout and addition of specific DNA fragments, and bringing a revolutionary revolution in the medical field. CRISPR-Cas9 is the third generation of gene editing technology, known as the "genetic magic scissors."
The recent research published in this study is the use of CRISPR-Cas9, the idea is very straightforward, that is, rewriting the gene sequence of mutations in bone marrow hematopoietic stem cells, repairing the disease-causing mutant gene. Stem cells have the ability to self-replicate, so that, in theory, patients with sickle cell anemia can get rid of the disease.
With the deepening of the aging of society, the transformation of aging furniture around the aging population has been launched, and the aging furniture has also closely followed the needs of the elderly.
Due to the degradation of bones and joints of the elderly and the gradual weakening of the muscle strength of the waist, higher requirements are put forward for the seat, and the aging chair came into being.
The height of the aging chair should be slightly lower than the knee height of the elderly, and the sitting depth should be the same as the thigh.
In order to prevent the elderly from falling into the cushion, the cushion and backrest of the aging chair should be made of high-density high-rebound sponge, which is soft and hard to sit.
At the same time, the waist position of the backrest is raised to provide a certain support for the waist. With the soft cushion under the backrest, the lumbar spine fits the back leaning curve of the human body, providing strong support for the waist and keeping the body in the most comfortable state.
The aging chair should be made of skin-friendly, breathable, waterproof and easy-to-clean fabric, which can effectively protect the sensitive skin of the elderly.
TRUTECH CO., LTD. is an enterprise specializing in the research, development, production and sales of professional OTC products.The main products include shower chairs, armrests, toilet racks and toilet armrests, bedside armrests, elderly chairs and sofas, crutches and walking aids, knee pads, waist supports and other equipment.
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