Check saliva and detect Alzheimer's disease early

Release date: 2015-07-30

Early detection of Alzheimer's disease is now easier! According to the latest research report released by Canada, scientists can detect dementia early from the saliva that is at their fingertips. This test is non-invasive and helps early treatment and delays the deterioration of symptoms.

Identifying Alzheimer's disease

Alzheimer's disease is a very common degenerative dementia. The patient's brain nerve cells are destroyed and the brain is atrophied. The doctor can diagnose the protein by magnetic resonance imaging (MRI), positron photography (PET) patients' brains, and cerebrospinal fluid extraction. The most obvious early symptoms are memory loss, and problems with the identification of time, place, and characters. Former US President Reagan suffered from this disease.

"We are getting more and more understanding of Alzheimer's disease," said Sith Snyder, director of medical and scientific operations at the Alzheimer's Association. "There are studies that let us know that patients are beginning to experience memory loss and recognition. Before the problem, potential physiological changes began as early as a decade ago or longer. This study is dedicated to finding changes associated with Alzheimer's disease from saliva samples."

New saliva test

Researchers at the University of Alberta in Canada analyzed saliva samples, including 35 with normal cognitive ability, 25 with mild dementia, and 22 with Alzheimer's disease. Nearly 6,000 brain-related small molecules or metabolites were tested, and biomarkers with mild dementia and Alzheimer's disease were identified, and 27 other subjects were successfully detected using these biomarkers. .

"This test is very cheap, it helps us to detect the disease early, and helps us understand the pathogenesis process and mechanism, or advise patients to do other tests. Saliva is very easy to collect and," said Stadtakta, a researcher who published the study. Transportation, in addition to helping early detection of early prescription drugs, such testing methods can break the different limits of medical resources in different regions. However, experts also said that this method needs to invest more research as a medical test, in more subjects The accuracy and reproducibility of the test in the repeated test.

The study was published last week at the 2015 Alzheimer's Association International Symposium in Washington, DC.

Source: Bio 360

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