Cell wall breaking technology of ultrafine pulverizer

Ultra-fine pulverization technology and cell wall-breaking technology are newly developed Chinese medicine extraction technologies. Due to numerous advantages, development has always been a concern. Cell wall-breaking technology is a super-technical superfine pulverizing agent processing technology. For the clinical application of traditional Chinese medicine is a revolution, the Chinese herbal medicine cells break through the wall after ultra-fine pulverization, the drug effect release, the drug change, the treatment effect is better.

Generally, the size of human cells is 10-100 μm, the granulosa cells of ultrafine powder of Chinese medicine are 3-5 μm, and the cell scale of Chinese medicinal materials (plants and animals) is about 10-100 μm. Now common in Zui is the fineness of Chinese medicine pill powder at 150-180μm. The active ingredients of Chinese medicinal materials are usually intracellular and intercellular, respectively, mainly in the cell. If Chinese medicine is pulverized in a conventional manner, its individual particles are usually composed of several or dozens of cells, and the cell wall breaking rate is very low. The Chinese medicine cell cell wall breaking ultrafine pulverization processing technology can fully release the medicinal material components. After the cell wall, the water and oil in the cells migrate out, so that the surface of the microparticles is semi-wet. A stable particle cluster is formed between the particles and the particles, and each cluster contains the same proportion of Chinese medicine components.

The physical structure of the particle group varies with different combinations of HLB values ​​(hydrophilic, lipophilic balance), ductility, fragmentation, specific gravity, and different interactions of the components in the composition. This structure is conducive to the absorption and utilization of traditional Chinese medicine by the human body. The Chinese medicine has enhanced fat solubility and easily passes through the lipid membrane, which can quickly raise the blood concentration in the human body and achieve the purpose of healing.

The ultra-fine pulverization technology of Chinese medicinal materials is the national high-tech industrialization demonstration project and the “10th Five-Year” scientific and technological research project of the Ministry of Science and Technology. It can be widely used in the production of solid preparations such as granules, capsules, tablets, films, etc., and introduces ultrafine pulverization technology in some aspects of the preparation process, which can be used in solubility, disintegration degree, absorption rate, adhesion and Improve the quality of medicines and health products in terms of bioavailability.

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