British found that a protein can increase the chance of fertilization

Release date: 2012-09-25



Xinhua News Agency, London, September 21 (Reporter Huang Wei) For some infertile men, the cause of their fertility problem is the lack of a protein called PLCz in sperm. A research team in the United Kingdom announced that its members have been able to make this protein in the laboratory, and if it is added to the sperm, it is expected to increase the chance of egg fertilization.
Researchers from institutions such as Cardiff University in the UK reported in a new American journal, Fertility and Infertility, that sperm in the process of fertilizing eggs will inject a protein called PLCz into the egg, which will trigger A series of physiological responses necessary for the development of fertilized eggs. Some men are infertile because they lack this protein in their sperm, which causes sperm to develop into an embryo even if it is combined with an egg.
The researchers successfully produced active PLCz proteins in the laboratory. Experiments have shown that if it is injected into an unfertilized egg, the egg will have the same series of physiological responses as during normal fertilization, indicating that if the protein is added to the sperm with the corresponding defect, it is expected to greatly increase the chance of egg fertilization. .
The researchers said that the technology used in this experiment is not yet suitable for clinical applications, but its potential is obvious. In the future, it may be possible to add this protein in the artificial insemination process to help those who have corresponding defects and want children very much. people.

Source: Technology Daily

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